Sunday 24 January 2010

AKT Questions

1. A 41-year-old man has recently attended the surgery for fasting blood tests, including an oral glucose tolerance test, as part of his annual hypertension review. The following results are received:Fasting plasma glucose 5.9 mmol/l2 hour plasma glucose 9.6 mmol/lSerum total cholesterol 5.6 mmol/l (3.0–5.3 mmol/l)Serum triglycerides 2.2 mmol/l (0.5–2.0 mmol/l)Whati is the SINGLE MOST likely diagnosis in this patient? Select ONE option only.


A. Diabetes mellitus
B. Impaired fasting glycaemia
C. Impaired glucose tolerance
D. Metabolic syndrome
E. Normal glycaemic control

Answer: C

Diabetes mellitus is defined by:• Fasting glucose greater than or equal to 7.0 mmol/lL and• 2 hour glucose greater than or equal to11.1 mmol/lL
Impaired fasting glycaemia is defined by:• Fasting glucose greater than or equal to6.1 and less than < 7.0 mmol/lL and• 2 hour glucose < less than 7.8 mmol/lL
Impaired glucose tolerance is defined by:• Fasting glucose < less than 7.0 mmol/Ll and• 2 hour glucose greater than or equal to7.8 and < less than 11.1 mmol/lLThe
metabolic syndrome is a condition characterizsed by at least three of the following clinical features:• Central obesity• Elevated triglyceride• Low HDL cholesterol• Raised blood pressure• Raised fasting plasma glucoseNormal glycaemic control is defined by:• Fasting glucose less than or equal to 6.0 mmol/lL and• 2 hour glucose < less than 7.8 mmol/lL

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